The clip features Manson and Depp taking on the roles of Cain and Abel; the sons of Adam and Eve from the biblical Book of Genesis.
The intensely gluttonous video climaxes at the point when after their fued reaches its peak, Manson as Cain commits what appears to be the murder of Abel.
Marilyn Mason released his huge 10th studio album Heavey Upside Down last Friday, having scrapped the original title SAY10 and original release date of February.
This isn’t the first piece of video we’ve seen from Manson for ‘SAY10’. Last year he released some visuals for the track, featuring an effigy of a beheaded Donald Trump, in the lead up to the US Presidential Election.
The video has been released despite Marilyn Manson’s recent hospitalization after having a stage prop fall on him while he performed live in New York just over a week ago.
Watch the new clip for ‘SAY10’ featuring Johnny Depp below.